Also called: Quad screening, Quad marker test, 4-marker screen
Report
{context.blood_test.parameters} Parameters
What it checks
Report delivery
Test for
Age group
Commonly advised for
The Quadruple Test is a prenatal blood screening test performed during the second trimester of pregnancy to assess the risk of certain fetal chromosomal abnormalities and neural tube defects. It measures four biochemical markers in the mother's blood: AFP, hCG, estriol, and inhibin A.
This test does not diagnose conditions but estimates the probability of abnormalities.
Why Is This Test Recommended?
It is recommended for pregnant women between 15 and 20 weeks of gestation, especially those with advanced maternal age, family history of genetic disorders, or abnormal first-trimester screening results.
What Do the Results Indicate?
Abnormal levels may indicate increased risk for Down syndrome, Edwards syndrome, or neural tube defects. Normal results suggest low probability but do not completely rule out abnormalities.
How Is the Test Performed and Prepared For?
A blood sample is collected. No fasting is required. Accurate gestational age is crucial for correct interpretation.
Frequently Asked Questions (FAQs)
Is this a diagnostic test?
No, the Quadruple Test is a screening test, not a diagnostic test; it assesses risk probability and abnormal results require follow-up with diagnostic procedures like amniocentesis or detailed ultrasound for confirmation.
Does it harm the baby?
No, the test does not harm the baby as it only involves drawing blood from the mother; it is completely safe and non-invasive for both mother and fetus.
Can abnormal results be false?
Yes, abnormal results can be false positives, meaning the test indicates elevated risk even when the baby is healthy; factors like incorrect gestational age calculation or multiple pregnancy can affect accuracy.
What follows an abnormal result?
Further testing is recommended following an abnormal result, which may include detailed ultrasound examination, amniocentesis, or genetic counseling to confirm or rule out suspected abnormalities.
Is ultrasound also required?
Usually yes, ultrasound is typically required alongside the Quadruple Test to confirm gestational age, assess fetal anatomy, detect structural abnormalities, and provide comprehensive prenatal screening.
The Quadruple Screen is a second-trimester pregnancy screening test using four markers. It is meant for:
Tapadia Diagnostic Centre in Secunderabad offers NABL-accredited Quad Screen test from a Blood sample(s). Quad screening, Quad marker test, 4-marker screen is also prescribed for Risk of birth defects, genetic disorders. Established in 1989, this doctor-led diagnostic centre ensures high accuracy. Home sample collection and walk-in facility available at our Secunderabad center. Pay at the centre with no advance payment. Book online or visit us.
Sree Ranganatha Swamy Devasthanam, Yapral, H.No. 5-3-1, Bhagat Singh Nagar, Yapral
Services: Lab, ECG
Branch Incharge: Mr. Praveen Gupta : 9848056578
59/1/2(6-1R-002), Karkana,Secunderabad-09
Services: Lab, X Ray, ECG
Phone No: 9281063662
Branch Incharge: Mr. ASHOK : 9246846874
6-1-103, Ground Floor, Padma raonagar, Secunderabad.
Services: Lab, X Ray, ECG, U/S Scan
Phone No: 9390110059
Branch Incharge: Mr. Suman- 8179607955
Quad Screen in Secunderabad
Rated 4.6 on Google
From 6,477 patient reviews across our Hyderabad centres.
Every report, kept for you
Past reports stay in your account and can be downloaded again.
NABL accredited
Every result reviewed by a qualified pathologist before it reaches you.
Four decades of practice
A family-run diagnostic centre, trusted by doctors and households since 1989


HIV 1 & 2 Antibodies, Serum-Elisa Method in Secunderabad
Dengue IgG, IgM Antibodies + NS1 Antigen-Rapid, Serum in Secunderabad
Lipoprotein A (Lp A), Serum in Secunderabad
Erythrocyte Sedimentation Rate (ESR) in Secunderabad
Thyroxine Total (T4), Serum in Secunderabad
Triiodothyronine Total (T3), Serum in Secunderabad
CA 19.9 (Pancreatic Cancer Marker), Serum in Secunderabad
NIPT with Microdeletions in Secunderabad
NIPT Basic in Secunderabad
Complete Blood Picture (CBP) in Secunderabad
Serum Phosphorus Test in Secunderabad
TIBC in Secunderabad
Urology Profile in Secunderabad
Beta HCG Free, Serum (Pregnancy Test) in Secunderabad
Viral Screening in Secunderabad
AFP Test in Secunderabad
Microalbuminuria test in Secunderabad
Diabetes Testing (FBS + PLBS) in Secunderabad
Antithrombin III in Secunderabad
D-dimer test in Secunderabad
Creatine Kinase (CK) Test in Secunderabad
AST Test in Secunderabad
Cardiac Markers in Secunderabad
Pap Smear - LBC in Secunderabad
DVT Profile in Secunderabad
Bleeding Time and Clotting Time (BT & CT) in Secunderabad
Estradiol Test in Secunderabad
hs-CRP Test in Secunderabad
Alkaline Phosphatase (ALP) Test in Secunderabad
Fertility Profile in Secunderabad
Albumin blood test in Secunderabad
Troponin T in Secunderabad
Infertility Profile Extended in Secunderabad
Electrolyte Panel in Secunderabad
Anticardiolipin Antibodies (IgG) in Secunderabad
PSA Test in Secunderabad
FSH Test in Secunderabad
STD Panel in Secunderabad
PCOS Profile in Secunderabad
Serum Iron Test in Secunderabad
Cardiac Profile-III in Secunderabad
Plasma Fibrinogen Test in Secunderabad
HBsAg Test in Secunderabad
Cardiac Biomarker Test in Secunderabad
Herpes Simplex Virus (HSV) Types 1 and 2 Antibody Test in Secunderabad
Antenatal Profile in Secunderabad
Activated Partial Thromboplastin Time in Secunderabad
Lipid Panel in Secunderabad
Fine Needle Aspiration Cytology in Secunderabad
CRP test in Secunderabad
Joint Pain / SLE / Collagen Profile-I in Secunderabad
PAPP-A Test in Secunderabad
Insulin Test in Secunderabad
Triple Screen Test in Secunderabad
Anti-HCV Test in Secunderabad
Basic Metabolic Panel (BMP) in Secunderabad
Very low-density lipoprotein (VLDL) test in Secunderabad
Free Testosterone in Secunderabad
Triglycerides Test in Secunderabad
Quad Screen in Secunderabad
Folic Acid in Secunderabad
Urinalysis in Secunderabad
CEA Test in Secunderabad
Ferritin Test in Secunderabad
Transferrin Saturation% in Secunderabad
Protein C Antigen in Secunderabad
Alpha Feto Protein (AFP) - Fluid in Secunderabad
CPK (MB) Test in Secunderabad
Lupus Anticoagulant Testing in Secunderabad
Reticulocyte Count in Secunderabad
Infertility Profile-Basic in Secunderabad
Beta hCG Test in Secunderabad
DIABETIC PROFILE in Secunderabad
LH Test in Secunderabad
Anti-Müllerian Hormone (AMH) Test in Secunderabad
Bile Salts and Bile Pigments, Urine in Secunderabad
HbA1c in Secunderabad
Vitamin D (1,25-Dihydroxyvitamin D) in Secunderabad
Liver Function Test (LFT) in Secunderabad
Anemia Profile Basic in Secunderabad
Rheumatoid Factor in Secunderabad
Widal Test in Secunderabad
Bilirubin blood test in Secunderabad
Inhibin A, Tumor Marker, Serum in Secunderabad
Thyroid Function Tests in Secunderabad
eGFR in Secunderabad
Menopause Profile in Secunderabad
EXTENDED DIABETIC PROFILE in Secunderabad
LDH Test in Secunderabad
Total Cholesterol Test in Secunderabad
Random Blood Sugar Test in Secunderabad
Total Protein Test in Secunderabad
RPR test in Secunderabad
Anti-dsDNA Test in Secunderabad
HDL Cholesterol in Secunderabad
Blood Type Test in Secunderabad
ASO Titre in Secunderabad
Blood Urea(Serum) Test in Secunderabad
Postprandial Blood Sugar Test in Secunderabad
Back Pain Profile in Secunderabad
ANA test in Secunderabad
Serum Creatinine Test in Secunderabad
PT/INR Test in Secunderabad
Fasting Blood Sugar Test in Secunderabad
Extended Anemia Profile III Executive in Secunderabad
Kidney Function Test (Renal Profile) in Secunderabad
Serum Magnesium Test in Secunderabad
Well-woman exam in Secunderabad
LDL cholesterol test in Secunderabad
Prolactin Test in Secunderabad
Malaria Blood Smear in Secunderabad
Liver Function Test (+GGT) in Secunderabad
TPHA Test in Secunderabad
Hepatitis B Surface Antigen (HBsAg) Test in Secunderabad
Antenatal Profile 2 in Secunderabad
TSH Test in Secunderabad
Cardiac Catheterization in Secunderabad
Cardiolipin Antibody (IgM) in Secunderabad
Master Health Checkup in Secunderabad
Calcium Profile in Secunderabad
Coagulation Profile in Secunderabad
Uric Acid Test in Secunderabad
Vitamin D (25 - Hydroxy Vitamin D, Serum) in Secunderabad
Globulin Test in Secunderabad
Fever Profile Test in Secunderabad
Connective Tissue Disease Profile in Secunderabad
Calcium Blood Test in Secunderabad
IHC in Secunderabad
Estriol Unconjugated (E3) Test in Secunderabad
Blood Typing in Secunderabad
Vitamin B12 Test in Secunderabad
Serum Cortisol in Secunderabad
Double Marker Test in Secunderabad
Pap Smear, Conventional in Secunderabad
Protein S Activity in Secunderabad
Non-Invasive Prenatal Testing (NIPT) in Secunderabad
whole exome sequencing in Secunderabad
Newborn Screening (NBS) in Secunderabad
Renal Function Test (RFT) in Secunderabad