Also called: Quad screening, Quad marker test, 4-marker screen
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The Quadruple Test is a prenatal blood screening test performed during the second trimester of pregnancy to assess the risk of certain fetal chromosomal abnormalities and neural tube defects. It measures four biochemical markers in the mother's blood: AFP, hCG, estriol, and inhibin A.
This test does not diagnose conditions but estimates the probability of abnormalities.
Why Is This Test Recommended?
It is recommended for pregnant women between 15 and 20 weeks of gestation, especially those with advanced maternal age, family history of genetic disorders, or abnormal first-trimester screening results.
What Do the Results Indicate?
Abnormal levels may indicate increased risk for Down syndrome, Edwards syndrome, or neural tube defects. Normal results suggest low probability but do not completely rule out abnormalities.
How Is the Test Performed and Prepared For?
A blood sample is collected. No fasting is required. Accurate gestational age is crucial for correct interpretation.
Frequently Asked Questions (FAQs)
Is this a diagnostic test?
No, the Quadruple Test is a screening test, not a diagnostic test; it assesses risk probability and abnormal results require follow-up with diagnostic procedures like amniocentesis or detailed ultrasound for confirmation.
Does it harm the baby?
No, the test does not harm the baby as it only involves drawing blood from the mother; it is completely safe and non-invasive for both mother and fetus.
Can abnormal results be false?
Yes, abnormal results can be false positives, meaning the test indicates elevated risk even when the baby is healthy; factors like incorrect gestational age calculation or multiple pregnancy can affect accuracy.
What follows an abnormal result?
Further testing is recommended following an abnormal result, which may include detailed ultrasound examination, amniocentesis, or genetic counseling to confirm or rule out suspected abnormalities.
Is ultrasound also required?
Usually yes, ultrasound is typically required alongside the Quadruple Test to confirm gestational age, assess fetal anatomy, detect structural abnormalities, and provide comprehensive prenatal screening.
The Quadruple Screen is a second-trimester pregnancy screening test using four markers. It is meant for:
Tapadia Diagnostic Centre in Hyderabad offers NABL-accredited Quad Screen test from a Blood sample(s). Quad screening, Quad marker test, 4-marker screen is also prescribed for Risk of birth defects, genetic disorders. Established in 1989, this doctor-led diagnostic centre ensures high accuracy. Home sample collection and walk-in facility available at our Hyderabad center. Pay at the centre with no advance payment. Book online or visit us.
Below M.S Junior College, Near NMDC, (Old Universal Bakery building), Masab Tank Road, Hyderabad.
Services: Lab, X Ray, ECG, U/S Scan, 2D Echo, CT Scan, MRI
Branch Incharge: Md Uzaib- 7499267648
Beside Ramalayam Temple, Near Ramakrishna Medical Hall,Hyderabd-80
Services: Lab, ECG
Branch Incharge: Mr. Shobhan : 9391111847
H.No.1-84/A/1, Veera Reddy Nagar Colony, Beside Union Bank Boduppal, Hyderabad-500092
Services: Lab, X Ray, ECG
Branch Incharge: MR. Praveen Gupta : 9848056578
Quad Screen in Hyderabad
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Four decades of practice
A family-run diagnostic centre, trusted by doctors and households since 1989


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