Also called: Total protein test, Serum protein electrophoresis, Gamma gap
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Serum globulin measures the total globulin proteins in the blood, which include immunoglobulins (antibodies), enzymes, and carrier proteins. These proteins support immune defense, transport of hormones, and clotting functions.
Abnormal levels may indicate liver or kidney disease, immune disorders, infections, or certain cancers.
Evaluate immune system status
Monitor chronic infections
Investigate liver or kidney disease
Assess nutritional health
Track therapy response in chronic illness
Globulin is divided into alpha, beta, and gamma fractions. Each fraction performs distinct functions, from immunity to transport. Imbalances may point to inflammation, malignancy, or chronic illness.
Recurrent infections
Fatigue or weakness
Swelling or edema
Liver or kidney disease
No special preparation needed
Continue regular diet and medications
Normal: 2.0–3.5 g/dL
High: Chronic inflammation, multiple myeloma
Low: Liver disease, malnutrition, kidney loss
Can globulin levels change with infection?
Yes, globulin levels often rise during an infection as part of the body's immune response. Acute infections can cause a temporary increase in gamma globulins, while chronic infections may lead to sustained elevations. If you suspect an infection, consult your doctor for a comprehensive evaluation.
Is this test part of a liver panel?
Sometimes, yes—it can be included in a comprehensive liver function panel or metabolic panel, especially when assessing protein synthesis in the liver. However, it's not always a standard component, so specify your concerns to your healthcare provider to ensure it's ordered if needed.
Can dehydration affect results?
Mildly, yes—dehydration can concentrate the blood, leading to slightly higher globulin readings. To get the most accurate results, stay well-hydrated before the test unless otherwise instructed by your doctor.
Is fasting required?
No, fasting is not required for this test. You can eat and drink normally beforehand, making it convenient for routine check-ups.
Can supplements influence results?
Rarely, but certain supplements like high-dose protein powders or immune boosters might have a minor impact. Always inform your healthcare provider about any supplements you're taking to interpret results accurately.
Globulins are blood proteins involved in immunity and transport. This test is advised if:
Tapadia Diagnostic Centre in Warangal offers NABL-accredited Globulin Test test from a Blood sample(s). Total protein test, Serum protein electrophoresis, Gamma gap is also prescribed for Fatigue, jaundice, swelling, nausea, weight loss. Established in 1989, this doctor-led diagnostic centre ensures high accuracy. Home sample collection and walk-in facility available at our Warangal center. Pay at the centre with no advance payment. Book online or visit us.
Globulin Test in Warangal
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